Novel device based on indium oxide and platinum aims to improve early diagnosis
The air we exhale can reveal our health and even indicate diseases. For example, a reduced concentration of the hydrocarbon isoprene may suggest lung cancer. A research team led by China’s Zhejiang University has developed a nano-sensor specifically for this application, aiming to enable early diagnosis and improve the chances of recovery.
The device, based on different metals, including platinum and indium, is significantly more sensitive than previous isoprene sensors, with a detection limit of only two parts per billion, according to a study published in ACS Sensors. It is also highly selective, can distinguish isoprene effectively from other volatile substances, and tolerates the natural humidity in breath. This meets the strict requirements for lung cancer screening.
“Breakthrough for Non-Invasive Screening”
The researchers have advanced indium oxide-based sensors, which showed promise in earlier trials, as reported by Genetic Engineering & Biotechnology News. Platinum nanoclusters play a key role as a catalyst in activating isoprene detection.
Integrated into a portable device that directly displays the concentration of the compound, the sensor’s practical effectiveness was tested, successfully distinguishing between lung cancer patients and healthy individuals.
According to the researchers, this new sensor technology could be a breakthrough for non-invasive lung cancer screening, enabling fast and affordable diagnoses. However, further research is needed for commercialization, such as in sensor materials, data analysis, and integration into portable devices.
What Metals Can Achieve in Medicine: We have reported several times on the potential of indium, platinum, and similar materials for remarkable medical advances. Tiny solar cells in the eye, for example, could help counteract vision loss. Other exciting developments include implants that dissolve in the body after their purpose is fulfilled and materials that reconnect severed nerves.
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